Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal
Summary: The synergistic effect of alcohol and HCV mediated through TLR4 signaling transactivates NANOG, a pluripotency transcription factor Medical and Ambulatory supplies / Orthopedic important for the stemness of tumor-initiating stem-like cells (TICs).NANOG together with the PRC2 complex suppresses expression of oxidative phosphorylation (OXPHO